What is the substantia nigra pars compacta (SNc)?
The substantia nigra pars comapcta is a part of the substantia nigra. (1)

What is NOT the substantia nigra pars compacta?
The substantia nigra pars reticulata

What does the substantia nigra pars compacta contain?
it is densely packed with dopamine-producing neurons. (1)

The loss of nigrostriatal neurons in the substantia nigra pars compacta is a hallmark of Parkinson’s disease, leading to the characteristic motor symptoms of this disorder. (2)


Resources
1. ChatGPT 4, 6/3/23, “What is the substantia nigra?”
2. ChatGPT 4, 6/3/23, “Are the dopaminergic neurons that are located in the substantia nigra called something special?”

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